Sunday, July 17, 2011

Are grandparents safer drivers than mom and dad? (AP)

CHICAGO � Kids may be safest in cars when grandma or grandpa are driving instead of mom or dad, according to study results that even made the researchers do a double-take.

"We were surprised to discover that the injury rate was considerably lower in crashes where grandparents were the drivers," said Dr. Fred Henretig, an emergency medicine specialist at Children's Hospital of Philadelphia and the study's lead author.

Previous evidence indicates that car crashes are more common in older drivers, mostly those beyond age 65. The study looked at injuries rather than who had more crashes, and found that children's risk for injury was 50 percent lower when riding with grandparents than with parents.

The results are from an analysis of State Farm insurance claims for 2003-07 car crashes in 15 states, and interviews with the drivers. The data involved nearly 12,000 children up to age 15.

Henretig, 64, said the study was prompted by his own experiences when his first grandchild was born three years ago.

"I found myself being very nervous on the occasions that we drove our granddaughter around and really wondered if anyone had ever looked at this before," he said.

Reasons for the unexpected findings are uncertain, but the researchers have a theory.

"Perhaps grandparents are made more nervous about the task of driving with the `precious cargo' of their grandchildren and establish more cautious driving habits" to compensate for any age-related challenges, they wrote.

The study was released online Monday in the journal Pediatrics.

Northwestern University Professor Joseph Schofer, a transportation expert not involved in the research, noted that the average age of grandparents studied was 58.

"Grandparents today are not that old" and don't fit the image of an impaired older driver, he said. "None of us should represent grandparents as kind of hobbling to the car on a walker."

Grandparents did flub one safety measure. Nearly all the kids were in car seats or seat belts, but grandparents were slightly less likely to follow recommended practices, which include rear-facing backseat car seats for infants and no front-seats. But that didn't seem to affect injury rates.

Only about 10 percent of kids in the study were driven by grandparents, but they suffered proportionately fewer injuries.

Overall, 1.05 percent of kids were injured when riding with parents, versus 0.70 percent of those riding with grandparents, or a 33 percent lower risk. The difference was even more pronounced � 50 percent � when the researchers took into account other things that could influence injury rates, including not using car seats, and older-model cars.

Kids suffered similar types of injuries regardless of who was driving, including concussions, other head injuries and broken bones.

The study does not include data on deaths, but Henretig said there were very few. It also lacked information on the types of car trips involved; for example, driving in busy city traffic might increase chances for crashes with injuries.

Schofer, the Northwestern professor, said other unstudied circumstances could have played a role. For example, grandparents could be less distracted and less frazzled than busy parents dropping their kids off at school while rushing to get to work or to do errands. Driving trips might be "quality time" for older drivers and their grandchildren, Schofer said.

___

Online:

Pediatrics: http://www.pediatrics.org

American Academy of Pediatrics car seat recommendations: http://bit.ly/rqmKhT



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Falls, eye test may give clues to Alzheimer's (AP)

PARIS � Scientists in Australia are reporting encouraging early results from a simple eye test they hope will give a noninvasive way to detect signs of Alzheimer's disease.

Although it has been tried on just a small number of people and more research is needed, the experimental test has a solid basis: Alzheimer's is known to cause changes in the eyes, not just the brain. Other scientists in the United States also are working on an eye test for detecting the disease.

A separate study found that falls might be an early warning sign of Alzheimer's. People who seemed to have healthy minds but who were discovered to have hidden plaques clogging their brains were five times more likely to fall during the study than those without these brain deposits, which are a hallmark of Alzheimer's.

Both studies were discussed Sunday at the Alzheimer's Association International Conference in France.

More than 5.4 million Americans and 35 million people worldwide have Alzheimer's, the most common form of dementia. Brain scans can find evidence of it a decade or more before it causes memory and thinking problems, but they're too expensive and impractical for routine use. Doctors and families need easier ways to tell who is developing the disease, so a simple eye test and warning signs like falls could be a big help.

The eye study involved photographing blood vessels in the retina, the nerve layer lining the back of the eyes. Most eye doctors have the cameras used for this, but it takes a special computer program to measure blood vessels for the experimental test doctors are using in the Alzheimer's research, said the study's leader, Shaun Frost of Australia's national science agency, CSIRO.

Reseachers compared retinal photos of 110 healthy people, 13 people with Alzheimer's and 13 others with mild cognitive impairment, or "pre-Alzheimer's," who were taking part in a larger study on aging. The widths of certain blood vessels in those with Alzheimer's were different from vessels in the others and the amount of difference matched the amount of plaque seen on brain scans.

More study is planned on larger groups to see how accurate the test might be, Frost said.

Earlier work by Dr. Lee Goldstein of Boston University showed that amyloid, the protein that makes up Alzheimer's brain plaque, can be measured in the lens of the eyes of some people with the disease, particularly Down syndrome patients who often are prone to Alzheimer's.

A company he holds stock in, Neuroptix, is testing a laser eye scanner to measure amyloid in the eyes. Goldstein praised the work by the Australian scientists.

"It's a small study" but "suggestive and encouraging," he said. "My hat's off to them for looking outside the brain for other areas where we might see other evidence of this disease."

Eye doctors often are the first to see patients with signs of Alzheimer's, which can start with vision changes, not just the memory problems it's most known for, said Dr. Ronald Petersen, a Mayo Clinic dementia expert with no role in the new studies.

Other signs could be balance and gait problems, which may show up before mental changes do. Susan Stark of Washington University in St. Louis led the first study tying falls to a risk of developing Alzheimer's disease before mental changes show up.

It involved 125 people, average age 74, who had normal cognition and were taking part in a federally funded study of aging. They kept journals on how often they fell, and had brain scans and spinal taps to look for various substances that can signal Alzheimer's disease.

In six months, 48 fell at least once. The risk of falling was nearly three times greater for each unit of increase in the sticky plaque that scans revealed in their brains.

"Falls are tricky" because they can be medication-related or due to dizziness from high blood pressure, a blood vessel problem or other diseases like Parkinson's, said Creighton Phelps, a neuroscientist at the National Institute on Aging.

Falls also can cause head injury or brain trauma that leads to cognitive problems, said Laurie Ryan, who oversees some of the institute's research grants but had no role in the study. Older people who hit their heads and suffer a small tear or bleeding in the brain might seem fine but develop symptoms a month later, she said.

The bottom line: "If you see somebody who's having falls for no particular reason," the person should be evaluated for dementia, said William Thies, the Alzheimer's Association's scientific director.

The warning signs of Alzheimer's:

_Memory loss that disrupts daily life

_Trouble planning or solving problems

_Difficulty completing tasks

_Confusion with time or place

_Trouble understanding images and spatial relationships

_New problems with speaking or writing words

_Misplacing things and inability to retrace steps

_Decreased or poor judgment

_Social withdrawal

_Changes in mood or personality

___

Online:

National Institute on Aging: http://www.nia.nih.gov/Alzheimers

Alzheimer's Association: http://www.alz.org

___

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP



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Friday, July 15, 2011

1st patient with man-made windpipe almost said no (AP)

REYKJAVIK, Iceland � The first person to receive an artificial windpipe says he almost refused the lifesaving operation.

Doctors in Sweden announced last week they had transplanted a laboratory-made windpipe into Andemariam Teklesenbet Beyene, a 36-year-old Eritrean. While studying at a university in Iceland, he was diagnosed with advanced cancer and had a large tumor almost completely blocking his windpipe.

His Icelandic doctor referred Beyene to Dr. Paolo Macchiarini, a surgeon at Stockholm's Karolinska Institute who has done windpipe transplants in the past. Macchiarini suggested replacing Beyene's damaged windpipe with one made in a laboratory. "He explained that this has never been done to human beings," Beyene told the Associated Press Thursday. "I said, 'Oh my God.' If this has not been done, how can I agree to this?"

But after talking to his Icelandic doctor and to his family, including his wife and two children in Eritrea, Beyene agreed to the revolutionary transplant. "Then I just prayed and accepted it," he said. "I was happy with the operation."

Beyene's new windpipe was made using a spongy, plastic polymer to speed cell growth. The device has previously been used in tear ducts and blood vessels. Once the windpipe was constructed in the laboratory, Beyene's own stem cells were used to create millions of other cells to line and coat the windpipe. That meant Beyene's body wouldn't reject the new organ and that he doesn't need to take anti-rejection medicines.

Other windpipe transplants have been performed using donor windpipes and the patient's own stem cells to cover the new trachea, but Beyene's case is the first to use a man-made organ.

Beyene recently arrived back in Reykjavik and is now recovering at the national hospital. His doctors will run scans on his new windpipe every six months for at least the next five years. They will be monitoring Beyene for any possible complications, including possible infections.

Beyene isn't sure when he will be released from the hospital but hopes to return to Eritrea to see his family soon. "I am very eager to see them and they are very eager to see me," he said. "But it depends on the health situation."



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UN reports measles outbreaks in Ethiopia, Kenya (AP)

GENEVA � United Nations officials say outbreaks of measles in Ethiopia and Kenya have killed dozens of children and sickened thousands of others.

UNICEF spokeswoman Marixie Mercado said Friday at least 17,584 measles cases, including 114 deaths, have been reported by Ethiopian health officials in the first half of the year.

World Health Organization spokesman Tarek Jasarevic says at least 462 cases of measles, including 11 deaths, have been confirmed in recent months among Somali refugee children in the Kenyan refugee complex known as Dadaab.

He says 2 million children in Ethiopia are at risk of contracting measles.

WHO has warned that the movement of people and poor sanitation in overcrowded camps and towns due to drought and violence in East Africa increases the risk of cholera, typhoid and measles epidemics.



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Philippines warns against gecko as AIDS treatment (AP)

MANILA, Philippines � The Philippines warned Friday against using geckos to treat AIDS and impotence, saying the folkloric practice in parts of Asia may put patients at risk.

Environmental officials have also expressed alarm about the growing trade in the wall-climbing lizards in the Philippines. An 11-ounce (300-gram) gecko reportedly sells for at least 50,000 pesos ($1,160).

Geckos are reportedly exported to Malaysia, China and South Korea, where they are used as aphrodisiacs and as traditional medicine for asthma, AIDS, cancer, tuberculosis and impotence.

A health department statement said Friday that the use of geckos as treatments has no scientific basis and could be dangerous because patients might not seek proper treatment for their diseases.

"This is likely to aggravate their overall health and put them at greater risk," it added.

Treatments for asthma are easily available and affordable, while there are antiviral drugs to control the progress of HIV, it added.

Geckos are carnivorous, nocturnal reptiles from the family Gekkonidae that are found in tropical countries. They are known for their sticky footpads that allow them to climb vertical surfaces, including glass.

Wildlife official Mundita Lim said her office has asked law enforcers to look into the possibility that scammers may have infiltrated the trade because of the exorbitant prices being quoted online by buyers demanding geckos weighing at least 400 grams (14 ounces).

She said geckos in the wild grow up to 200 grams (7 ounces). Those fattened in captivity can grow only up to 300 grams (10 ounces).

Environment Secretary Ramon Paje earlier warned that collecting and trading geckos without permit can be punishable by up to four years in jail and a fine of up to 300,000 pesos ($6,900).

He said a healthy population of geckos is needed to regulate pests and maintain the fragile ecosystem. Geckos feed on insects and worms. Larger species hunt small birds and rodents.



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Thursday, July 14, 2011

German farm in deadly E. coli outbreak to reopen (AP)

BERLIN � German authorities say a farm involved in a deadly E. coli outbreak is being cleared to reopen following thorough testing and the removal of all fenugreek seeds � considered the likely source.

The outbreak was traced in early June to the vegetable sprout farm at Bienenbuettel, south of Hamburg. European authorities later said one batch of fenugreek seeds from Egypt was probably the source of the bacterial outbreak that killed 53 people � 51 in Germany, and one each in Sweden and the U.S.

The state agriculture ministry in Lower Saxony said Thursday that there is no further need to keep the farm closed after negative tests on all employees and possible sources of infection there. It said all stocks of fenugreek seeds were removed from the farm.



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