Friday, July 29, 2011

Nigeria parents risk jail for skipping polio shots (AP)

KANO, Nigeria � Officials in northern Nigeria say parents who do not allow their children to be vaccinated against polio now risk jail time for defying a government order.

The Kano state government says parents who prevent their children from getting immunized during the four-day campaign will face prosecution.

The campaign is targeting about 6 million children in the state, which recently recorded new polio cases.

Polio is largely eradicated in most of the world, but the vaccine has been met with resistance in Nigeria's impoverished north.

One 45-year-old local politician told The Associated Press on Friday that he would not allow his three young children to be immunized, saying he is skeptical of the vaccine.



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J&J cuts maximum Tylenol dose to prevent overdoses (AP)

TRENTON, N.J. � Johnson & Johnson said Thursday that it's reducing the maximum daily dose of its Extra Strength Tylenol pain reliever to lower risk of accidental overdose from acetaminophen, its active ingredient and the top cause of liver failure.

The company's McNeil Consumer Healthcare Division said the change affects Extra Strength Tylenol sold in the U.S. � one of many products in short supply in stores due to a string of recalls.

Starting sometime this fall, labels on Extra Strength Tylenol packages will now list the maximum daily dose as six pills, or a total of 3,000 milligrams, down from eight pills a day, or 4,000 milligrams. Beginning next year, McNeil will also reduce the maximum daily dose for its Regular Strength Tylenol and other adult pain relievers containing acetaminophen, the most widely used pain killer in the country.

Besides Tylenol, acetaminophen is the active ingredient in the prescription painkillers Percocet and Vicodin and in some nonprescription pain relievers, including NyQuil and some Sudafed products. It's found in thousands of medicines taken for headaches, fever, sore throats and chronic pain.

But people taking multiple medicines at once don't always realize how much acetaminophen they are ingesting, partly because prescription drug labels often list it under the abbreviation "APAP."

Two years ago, a panel of advisers to the Food and Drug Administration called for sweeping restrictions to prevent accidental fatal overdoses of acetaminophen.

Then in January, the FDA said it would cap the amount of acetaminophen in Vicodin, Percocet and other prescription pain killers at 325 milligrams per capsule � just under half the 700 milligram maximum of some products on the market then. The agency also said it was working with pharmacies and other medical groups to develop standard labeling for acetaminophen.

"Acetaminophen is safe when used as directed," Dr. Edwin Kuffner, McNeil's head of over-the-counter medical affairs, said in a statement. "McNeil is revising its labels for products containing acetaminophen in an attempt to decrease the likelihood of accidental overdosing."

Excessive use of acetaminophen can cause liver damage. In the U.S., it's blamed for about 200 fatal overdoses and sends 56,000 people to the emergency room each year.

McNeil spokeswoman Bonnie Jacobs said other makers of pain relievers are likely to make similar changes to their product labels.

Extra Strength Tylenol is manufactured at a J&J factory in Las Piedras, Puerto Rico, where production has been decreased for months because the FDA, concerned about manufacturing and quality problems, is requiring additional reviews and approvals before medicines can be shipped. J&J said shipments of Extra Strength Tylenol should ramp up in the latter part of this year and throughout next year.

Las Piedras is one of three factories implicated in most of the 25 Johnson & Johnson recalls since September 2009, involving tens of millions of bottles of Tylenol and other nonprescription drugs made by McNeil. Several prescription drugs, hip implants and contact lenses made by other J&J subsidiaries also have been recalled.

The recalls, for quality problems ranging from metal shavings and improper levels of active ingredients in some medicines to packaging with a nauseating odor, resulted in a consent decree between McNeil and the FDA this spring.

As a result, Las Piedras and a second factory, in Lancaster, Pa., are under additional scrutiny. The third factory, in Fort Washington, Pa., made children's medicines such as liquid Tylenol. It has been closed since April 2010 and is being gutted and completely rebuilt.

Jacobs said the label changes are not related to the recalls.



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Thursday, July 28, 2011

CDC: Strokes rise among pregnant women, new moms (AP)

Strokes have spiked in the U.S. among pregnant women and new mothers, probably because more of them are obese and suffering from high blood pressure and heart disease, researchers report.

Hospitalizations for pregnancy-related strokes and "mini strokes" jumped from about 4,100 in 1994-95 to around 6,300 in 2006-07, a 54 percent increase, researchers said, extrapolating from figures in a large federal database.

"That is a very, very alarm-raising statistic that we need to take extremely seriously," said Dr. Olajide Williams, a neurologist at Columbia University and Harlem Hospital and an American Stroke Association spokesman. "We need to be more aggressive in screening these women for these risk factors."

The number of strokes is small, considering that around 4 million babies are born each year in the U.S. But pregnancy raises a woman's risk of a stroke because of all the hormone and blood changes that occur. If she starts out unhealthy, with a problem like diabetes or high blood pressure, she doubles her risk of suffering a stroke during or right after pregnancy, said Dr. Elena Kuklina, a stroke prevention expert at the Centers for Disease Control and Prevention.

She led the study, published Thursday in the American Heart Association journal Stroke.

Researchers used records from a sample of hospitals in nearly all states, covering up to 8 million hospitalizations each year. They looked at the number of women having strokes or transient ischemic attacks � TIAs, or "mini strokes" � while pregnant or in the three months after childbirth.

Rates were highest in the South and lowest in the Northeast.

Researchers also looked at the prevalence of high blood pressure and heart disease, health problems closely related to obesity, and concluded that this accounted for nearly all the rise in stroke-related hospitalizations. Researchers also noted that women are having children at later ages, and the risk of a stroke rises with age.

Sometimes pregnant women and new moms are so focused on the baby's health that they neglect to consider their own, Williams said.

"They're thinking about the baby's name, the special room and what color they're going to paint the room. They're thinking about motherhood," Williams said. "But an ounce of prevention is always the best recipe for a healthy life."

Kuklina agreed.

"If you plan a pregnancy, try to see your physician before you get pregnant" to be assessed for stroke risks, she advised. And if you are pregnant, "try to start your prenatal care as early as possible. It's important to live healthy lives, to have healthy diets, stop smoking if you are smoking, increase your physical activity and maintain your healthy weight before pregnancy and continue during pregnancy."

Earlier this year, CDC researchers using the same hospitalization records reported that strokes are rising dramatically among young and middle-aged Americans while dropping in older people, a sign that the obesity epidemic may be starting to shift the age burden of the disease.

Getting help fast, as soon as symptoms appear, is key to preventing long-term damage. The warning signs of a stroke are sudden onset of any of these: numbness or weakness on one side, severe headache with no known cause, confusion, and trouble walking, speaking or seeing.

___

Online:

Stroke information: http://www.strokeassociation.org and http://stroke.nih.gov

___

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP



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Offensive launched to protect Somali relief effort (AP)

MOGADISHU, Somalia � African Union forces have launched an offensive in Somalia's capital so aid agencies can get emergency food supplies to thousands of starving people without coming under attack from al-Qaida-linked militants, an official said Thursday.

The al-Shabab fighters already have killed men who tried to escape the famine with their families, saying it is better to starve than accept help from the West.

Lt. Col. Paddy Ankunda said Thursday that AU peacekeeping forces have conducted a "short tactical offensive operation" in Mogadishu.

"This action will further increase security ... and ensure that aid agencies can continue to operate to get vital supplies to internally displaced," he said.

The devastating famine in the Horn of Africa threatens al-Shabab's hold on areas under its control, with the militants fearing that the disaster will drive away the people they tax and conscript into military service.

In the past, the militants have blocked aid workers from helping those in need in Somalia, fearing that foreign assistance would undermine their control.

A World Food Program plane with 10 tons of peanut-butter paste landed Wednesday in Mogadishu, the first of several planned airlifts in coming weeks.

That will help, but Lt. Col. Kuamurari Katwekyeire, the civil-military coordination chief for the African Union Mission in Somalia, known as AMISOM, said the U.N. and other aid groups need to do more.



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Wednesday, July 27, 2011

Food supplements airlifted into famine-hit Somalia (AP)

MOGADISHU, Somalia � A plane carrying 10 tons of urgently needed nutritional supplements to treat malnourished children has landed in famine-hit Somalia, a U.N. official said Wednesday.

The airlift is part of a crisis intervention as famine threatens to spread across lawless Somalia.

David Orr, a World Food Program spokesman who flew with the shipment from neighboring Kenya to the Somali capital of Mogadishu, said it was the first airlift of food aid since the U.N. declared a famine in parts of Somalia last week.

Orr said the aid would be distributed to medical facilities to treat the malnourished children.

WFP spokeswoman Challiss McDonough said this is first of several planned airlifts in coming weeks. She said Wednesday's shipment of peanut butter-based nutritional paste will treat 3,500 malnourished children for one month.

McDonough said WFP decided to send in the airlift because of an urgent need to treat the growing number of internally displaced children suffering from malnutrition before their condition deteriorates.

She said about 18,000 children are suffering from malnutrition and that the number is expected to grow to 25,000.

WFP says it cannot reach 2.2 million people in need of aid in the militant-controlled areas in southern Somalia because of insecurity.

Somalia has been embroiled in conflict for two decades, since the last leader was overthrown by warlords who then turned on each other. Islamist militant groups have spent the last few years battling the weak U.N.-backed government in an attempt to overthrow it.

Al-Shabab � the most dangerous militant group in Somalia � said last week it will not allow the aid groups to operate in its territories, exacerbating the drought crisis.

Earlier this month al-Shabab, which has links to al-Qaida, had shown indications of wavering on its 2009 ban on certain aid groups in its territories.

The drought has created a triangle of hunger where the borders of Ethiopia, Kenya and Somalia meet. WFP estimates more than 11.3 million people need aid across drought-hit regions in East Africa. The majority of those affected live in pastoral communities whose herds have been wiped out because of a lack of water.

Separately, UNICEF said Wednesday that it is trying to vaccinate more than 300,000 children in Kenya in an emergency program designed to prevent an outbreak of disease as refugees stream into northern Kenya.

Jayne Kariuki from UNICEF said that four northern Kenyan regions will be targeted along with Dadaab, the world's largest refugee camp, during the two-week program to immunize the children against polio and measles.

The children will also receive vitamin A and de-worming tablets. In Liboi, a dusty town in Kenya near the border with Somalia, mothers in long robes clustered around with children as aid workers dispensed medicine under a thorn tree.

Kenya recorded it first polio case infection in 20 years in 2009, after a four-year-old girl was diagnosed with the disease along the country's remote border with Sudan.

Polio is an infectious disease that mainly strikes children under five. It causes paralysis and can be fatal.

In 2006, two refugees escaping the war in Somalia were diagnosed with the disease at the Dadaab refugee camp at Kenya's eastern border with Somalia. That outbreak was contained before it spread.

___

Tom Odula in Nairobi, Kenya, and Katharine Houreld in Liboi contributed to this report.



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For some, hypnosis eases pain, recovery of surgery (AP)

LONDON � As the surgeons cut into her neck, Marianne Marquis was thinking of the beach.

As she heard the doctors' voices, she was imagining her toes in the sand, the water lapping.

Marquis had been hypnotized before surgery to have her thyroid removed. She's among a growing number of surgical patients at the Belgian hospital, Cliniques Universitaires St. Luc in Brussels, who choose hypnosis and a local anesthetic to avoid the groggy knockout effect of general anesthesia.

These patients are sedated but aware, and doctors say their recovery time is faster and their need for painkillers reduced. This method is feasible for only certain types of operations.

In her case, Marquis, 53, imagined herself in a field near a beach � which her anesthetist began describing by whispering into her ear about 10 minutes before surgery. She remembers hearing the doctors talk to her, but said it was as if they were far away.

"I was imagining squishing my toes in the sand and feeling water come up over them," Marquis said. She felt a little pressure on her neck with the first incision but said it wasn't painful.

Since doctors began offering hypnosis at the hospital in 2003, hundreds of patients have chosen it. At another Belgian hospital, more than 8,000 surgeries have been done this way since 1992.

Doctors say nearly any surgery usually done with a local anesthetic could work with hypnosis and less pain medicine. Proponents say hypnosis can dull patients' sense of pain and that it also cuts down on the need for anesthetic.

That means patients recover faster and hospitals save money, according to some studies. But it may require doctors to spend more time with patients beforehand to do the hypnosis and they may need more careful monitoring during surgery.

The technique has become increasingly popular in France and Belgium in recent years. Some plastic and facial surgeons in Germany also use hypnosis, as well as some British dental surgeons.

The French Society of Anesthesiologists describes hypnosis as a valid way to supplement anesthesia to reduce stress, anxiety and pain but neither the Belgian nor British anesthesiology groups offer specific hypnosis advice. Because of demand, the French Society of Anesthesiologists created a special hypnosis branch in their organization last year.

There are no figures on how widely hypnosis is used across Europe. In several of the nearly dozen French hospitals in Rennes, a northwest city of about 200,000 people, it's used in about half of all operations, says Claude Virot, a psychiatrist and director of the Institute of Research and Training in Therapeutic Communication there. Virot helps organize hypnosis training and said about 500 health professionals get it every year in France.

Dr. Fabienne Roelants, Marquis' anesthetist, described hypnosis as a modified state of consciousness. "The patient's mind goes to a pleasant place, but the body stays in the operating room." At Roelants' hospital, one-third of all surgeries to remove thyroids and one-quarter of all breast cancer surgeries, including biopsies and mastectomies, use hypnosis and local anesthetic. She and colleagues hope to expand the technique to procedures like hernias, knee arthroscopies and plastic surgeries.

Roelants said if patients feel any pain during the procedure, anesthetists immediately give them a painkiller shot.

During a recent procedure in Brussels where Christel Place, 43, had her thyroid removed, she furrowed her brow a couple of times to signal to Roelants she needed more drugs. In a green-lit room that helps relax the patients, Place pictured herself hiking in the French Alps while surgeons sliced her neck open.

The thyroid is a small gland at the bottom of the neck and makes hormones to control the body's metabolism. It is sometimes removed when it becomes enlarged, overactive or cancerous. The surgery can be done either with local or general anesthesia and is considered low-risk.

Place said waking up from the surgery was more abrupt than she'd expected. "It was like I was really in the mountains and then 'poof,' it was over," Place said, laughing.

Other experts caution that hypnosis would be impossible in major operations involving the heart or other internal organs because the pain would be unbearable.

"If hypnosis doesn't work and you've got somebody's abdomen or chest open, then you're in big trouble," said George Lewith, a professor of health research at Southampton University. "You need to be able to switch to another option immediately," he said.

Consistency is also an issue. "It's not used routinely because it's not effective in everyone and it takes a while," said Dr. Mark Warner, president of the American Society of Anesthesiologists. He said doctors would need extra time to conduct hypnosis and would need to work more closely with surgeons.

Warner said there are no guidelines on its surgical use in the U.S. He often uses music therapy or asks patients to picture a soothing scene to distract them from any discomfort. "If we could get more research on the right patient groups that would benefit from (hypnosis), that would be wonderful," he said.

Some experts said hypnosis is a hard sell because no one really profits from it.

"The problem is the money doesn't really go into anyone's hands, and the only person who really benefits from it is the patient," said Guy Montgomery, an associate professor at the Mount Sinai Medical Center in New York, who led a study published in the Journal of the National Cancer Institute in 2007.

In that research, Montgomery and colleagues randomly assigned 200 patients in the U.S. having a breast biopsy or lumpectomy to either get hypnosis or a brief session with a psychologist beforehand. They found hypnotized patients needed fewer painkillers and sedatives and required less time in surgery. On average, each hypnotized patient cost the hospital about $770 less than those who weren't hypnotized.

Marquis recommends hypnosis to patients who want to avoid anesthesia, but warned it isn't for everyone.

"You have to be in the right mental frame of mind for this, be properly prepared and trust the medical staff to take care of you," she said. "If you're very skeptical of hypnosis and freaked out about whether it's going to work, it probably won't."



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