Monday, June 20, 2011

Study: Docs overtesting for cervical cancer virus (AP)

WASHINGTON � Too many doctors are testing the wrong women, or using the wrong test, for a virus that causes cervical cancer.

The days of one-size-fits-all screening for cervical cancer are long gone. How often to get a Pap smear � and whether to be tested for the cancer-causing HPV virus at the same time � now depend on your age and other circumstances.

But a government study reports Monday that a surprising number of doctors and clinics aren't following guidelines from major medical groups on how to perform HPV checks, suggesting a lot of women are getting unnecessary tests.

That wastes money and could harm women who wind up getting extra medical care they didn't need, says Dr. Mona Saraiya of the Centers for Disease Control and Prevention, who led the research.

Even she wasn't protected from the confusion. Saraiya was stunned to get a bill showing that her own doctor had ordered testing for HPV strains not connected to cervical cancer.

The findings, reported in the journal Obstetrics & Gynecology, show women have to be savvy to ensure they're getting the right checkups � enough, but not too much.

"It's extremely discouraging," says Debbie Saslow, gynecologic cancer director at the American Cancer Society, who's had to argue with her doctor against testing too often. "We have not been able to get that message across."

Cervical cancer grows so slowly that Pap smears � which examine cells scraped from the cervix � usually find it in time to treat, or even to prevent when precancerous cells are spotted and removed.

For decades, Paps were the only way to screen for cervical cancer. Now doctors know that certain strains of HPV, the human papillomavirus, cause most cervical cancer. HPV testing isn't a replacement for the Pap. But it can provide extra information to help determine if a woman is at higher or lower risk and thus guide her ongoing care � if it's used correctly.

The new CDC study, part of a national survey of medical practices that included 600 providers of cervical cancer screening, examined how doctors are using it.

The study found 60 percent of doctors and clinics say they give a routine Pap-plus-HPV test to women who are too young for that combination. Guidelines stress that so-called co-testing is only for women 30 and older. If both tests are negative, they can wait three years before their next screening.

Why the age limit? Saslow says HPV is nearly as common as the common cold, especially in younger women � but their bodies usually clear the infection on their own and only a years-long infection is risky. Learning that a 20-something has HPV increases the odds of more invasive testing that in turn can leave her cervix less able to handle pregnancy later in life. Younger women are supposed to get HPV testing only if a Pap signals a possible problem and doctors really need the extra information.

Then there's the question of which test to use. Only a few so-called high-risk strains of HPV cause cervical cancer, the strains doctors are supposed to test for. Before scientists understood the different HPV types, a test already was on the market that detects strains that can cause genital warts, not cervical cancer. The CDC's Saraiya says there's no reason to use that old test because learning you have a probably transient warts-causing strain doesn't alter your care.

Yet her study found 28 percent of doctors and clinics say they order tests for both the cancer-causing and warts-causing strains, regardless of patient age. The study couldn't tell why, although Saraiya says some doctors don't know there's a difference and some order forms for the lab tests don't differentiate.

An HPV test costs $80 to $100, on top of a $40 Pap. Saraiya says labs can bill for two HPV tests when doctors order testing for both kinds of strains.

So what does a woman need to know before her next checkup? The CDC has developed a consumer-friendly brochure to help women understand their options for cervical cancer screening: http://tinyurl.com/6g8de6v

And guidelines from the American College of Obstetricians and Gynecologists recommend that:

_Routine Paps start at age 21.

_Most women in their 20s get a Pap every two years.

_Women 30 and older wait three years between screenings if they've had a negative Pap and negative HPV test, or three consecutive clear Paps.

_If a Pap is inconclusive at any age, HPV testing may help rule out who needs further examination and who can just repeat a Pap in a year.

_Anyone who's been vaccinated against HPV, a relatively new vaccine, still must follow Pap screening guidelines for their age group.

_Higher-risk women, such as those with HIV or previous cervical abnormalities, need more frequent screening.

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EDITOR'S NOTE � Lauran Neergaard covers health and medical issues for The Associated Press in Washington.



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Study says 1 in 13 US children have food allergy (AP)

CHICAGO � Food allergies affect about one in 13 U.S. children, double the latest government estimate, a new study suggests.

The researchers say about 40 percent of them have severe reactions � a finding they hope will erase misconceptions that food allergies are just like hay fever and other seasonal allergies that are troublesome but not dangerous.

Overall, 8 percent of the children studied had food allergies; peanuts and milk were the most common sources. That translates to nearly 6 million U.S. children.

The most recent government estimate, from the Centers for Disease Control and Prevention, was based on in-home interviews and found that about 3 million children were affected, or about 4 percent. Other estimates based on different methods have ranged from 2 percent to 8 percent.

The new study, funded by an advocacy group, is based on online interviews with parents of kids younger than age 18 and involved 40,104 children. Research firm Knowledge Networks conducted the survey. Families were recruited through random telephone dialing.

Results were released online Monday in Pediatrics.

The findings suggest that food allergies affect two kids per classroom, said lead author Dr. Ruchi Gupta, a pediatrician and researcher with Chicago's Children's Memorial Hospital.

Dr. Calman Prussin, an investigator with the National Institute of Allergy and Infectious Diseases, said the study "confirms that food allergy is a substantial public health problem."

Prussin said differences in estimates are due to different survey methods and definitions of what constitutes a food allergy. He said the only way to know for sure how many kids are affected would be lab tests on scores of children, which isn't practical.

Because the new figure is within the range of previous estimates, he said the study doesn't mean prevalence has increased, although experts generally believe allergies including those to food are on the rise, Prussin noted.

He said some people mistake food intolerances for food allergies. For instance, many people are lactose intolerant, meaning they can't properly digest milk. That can cause bloating and digestive problems, but not an allergic reaction.

Typical signs of a true food allergy include skin rashes, wheezing, tightness in the throat or difficulty breathing.

The new survey asked parents whether their children had those symptoms � a big strength of the study, Prussin said.

Many children outgrow allergies to some foods, including eggs and wheat, but they're less likely to outgrow allergies to peanuts and other nuts.

The study was funded by the Food Allergy Initiative, a nonprofit advocacy group founded by parents of children with allergies.

Mary Jane Marchisotto, the group's executive director, said the study "paints a more comprehensive picture" of food allergies, and should help raise awareness.

The group, funded privately but without industry money, is working with the CDC on national guidelines on how to manage food allergies in schools, she said.

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Online:

Pediatrics: http://www.pediatrics.org

Food Allergy Initiative: http://www.faiusa.org

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AP Medical Writer Lindsey Tanner can be reached at http://www.twitter.com/LindseyTanner



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